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Primidone

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Primidone is an anticonvulsant of the pyrimidinedione class whose active metabolites, phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial, simple partials, generalized tonic-clonic seizures, myoclonic, akinetic seizures and since the 1980s it has been a valuable alternative to propranolol in the treatment of... Read enhanced Wikipedia article

Factz from Wikipedia: we found the following about Primidone  

caused :
disturbances, ataxia, dizziness, headache, nystagmus, drowsiness, necrolysis, dermatitis, syndrome, arthralgia, sedation, impotence and vomit.

Results for "Primidone caused disturbances"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused ataxia"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused dizziness"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused headache"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused nystagmus"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused drowsiness"

Primidone Primidone can cause drowsiness, listless, ataxia, visual disturbances, nystagmus, headache, and dizziness.

Results for "Primidone caused necrolysis"

Primidone Primidone also causes exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis.

Results for "Primidone caused dermatitis"

Primidone Primidone also causes exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis.

Results for "Primidone caused syndrome"

Primidone Primidone also causes exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis.

Results for "Primidone caused arthralgia"

Primidone In addition to all of the above, primidone can cause arthralgia.

Results for "Primidone caused sedation"

Primidone Primidone, like phenobarbital and the benzodiazepines, can also cause sedation in the newborn and also withdrawal within the first few days of life; phenobarbital is the most likely out of all of them to do that.

Results for "Primidone caused impotence"

Primidone A randomized controlled trial whose results were published in the July 1985 issue of The New England Journal of Medicine found that primidone was more likely to cause impotence than phenytoin, carbamazepine, or phenobarbital.

Results for "Primidone caused vomit"

Primidone Primidone can also cause vomiting; this happens in 1.0–0.1% of users.

treated :
athetosis, cerebral palsy and syndrome.

Results for "Primidone treated athetosis"

Primidone Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis.

Results for "Primidone treated cerebral palsy"

Primidone Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis.

Results for "Primidone treated syndrome"

Primidone Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis.

increased :
megaloblastic, clearance and rate.

Results for "Primidone increased megaloblastic"

Primidone In addition to increasing the risk of megaloblastic anemia, primidone, like other older anticonvulsants also increases the risk of neural tube defects, and like other enzyme-inducing anticonvulsants, it increases the likelihood of cardiovascular defects, and cleft lip without cleft palate.

Results for "Primidone increased clearance"

Primidone Clobazam decreases clearance of primidone, Mesuximide increases plasma levels of phenobarbital in primidone users, both primidone and phenobarbital accelerate the metabolism of carbamazepine via CYP3A4, and lamotrigine's apparent clearance is increased by primidone.

Results for "Primidone increased rate"

Primidone Tempelhoff and colleagues at the Washington University School of Medicine's Department of Anesthesiology reported in 1990 that primidone and other anticonvulsant drugs increase the amount of fentanyl needed during craniotomy based on the patient's heart rate.

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Wikipedia Articles

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    Primidone

    Primidone is an anticonvulsant of the pyrimidinedione class whose active metabolites, phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants.
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    List of drugs: Prb-Prn

    primidone (INN)
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    Primidone

    Pyrimidinedione

    Primidone
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    Phenylethylmalonamide

    Phenylethylmalonamide (PEMA) is a metabolite of primidone.
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    ATC code N03

    N03AA03 Primidone
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    Sultiame

    Sultiame taken together with primidone may lead to severe side-effects, including psychotic reactions.
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    Anticonvulsant

    See also the related drug primidone.
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    Stiripentol

    It appears to increase the potency of phenobarbital, primidone, phenytoin, carbamazepine, clobazam and diazepam.
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    Qualitest

    PRIMIDONE Tablets
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    Ethadione

    | Barbiturates | Barbexaclone · Metharbital · Methylphenobarbital · Pentobarbital · Phenobarbital · Primidone |

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