Finding:

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   Primidone

   ... also contribute to the increased rate of fractures by causing... placed on epileptic people.Increased fracture rate has also been reported for... ... Tempelhoff and colleagues at the Washington University School of Medicine's Department of Anesthesiology reported in 1990 that primidone and other anticonvulsant drugs increase the amount of fentanyl... the patient's heart rate.
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   Stiripentol

   This may be increased up to 100 mg/kg per day, with a maximum of 4g. The dose to be divided into two or three with meals. ... It appears to increase the potency of phenobarbital, primidone, phenytoin, carbamazepine, clobazam and diazepam.
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   Carbamazepine

   Increases in dose at a rate of 200 mg every 1–2 weeks may be required to achieve a stable seizure threshold. ... | Barbiturates | Barbexaclone · Metharbital · Methylphenobarbital · Pentobarbital · Phenobarbital# · Primidone |
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   Epilepsy

   In industrialized countries the incidence rate decreased in children but increased among the elderly during the three decades prior to 2003, for reasons not fully understood. ... [Expression error: Missing operand for > "Comparison of carbemazipine, phenobarbital, phenytoin, and primidone in complex partial seizures."].
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   Frontal lobe epilepsy

   Phenobarbital, Primidone and Vigabatrin can cause depression and suicidal tendencies. ... Current research on this topic is aimed at improving the technique in order to increase success rates as well as developing non-invasive forms of physiologic monitoring in order to determine the epileptogenic focus conclusively.
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   Folate deficiency

   In infants and children, folate deficiency can slow growth rate. ... anticonvulsant medications (such as phenytoin, and primidone)
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   Anticonvulsant

   Nitrazepam, temazepam, and especially nimetazepam are powerful anticonvulsant agents, however their use is rare due to an increased incidence of side effects and strong sedative and motor-impairing properties. ... Primidone (1952).
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   Sultiame

   Less common adverse effects include giddiness, rash, Stevens-Johnson syndrome, nausea, weight loss, leukopenia, headache, psychic changes, depression, drooling, increased pain, frequency of fits, insomnia, status epilepticus. ... Sultiame taken together with primidone may lead to severe side-effects, including psychotic reactions.
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   Prodrug

   Primidone is metabolized by cytochrome P450 enzymes into phenobarbital, which is major, and phenylethylmalonamide, which is minor. ... Lisdexamfetamine is metabolized in the small intestine to produce dextroamphetamine at a controlled (slow) rate for the treatment of attention-deficit hyperactivity disorder
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    Post-traumatic epilepsy

    Like anyone else, TBI survivors may suffer seizures due to factors including imbalances of fluid or electrolytes, epilepsy from other causes, hypoxia (insufficient oxygen), and ischemia (insufficient blood flow to the brain). ... Other drugs commonly used to treat PTE include clonazepam, phenobarbitol, primidone, gabapentin, and ethosuximide.

Explore the following pages on Powerset:

• Primidone,
• Stiripentol,
• Carbamazepine,
• Epilepsy,
• Frontal lobe epilepsy,
• Folate deficiency,
• Anticonvulsant,
• Sultiame,
• Prodrug,
• Post-traumatic epilepsy

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