Finding:

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   Receptor antagonist

   Altering the amount of antagonist used in the assay can alter the dose ratio. ... In functional assays using competitive antagonists, a parallel rightward shifts of agonist dose–response curves with no alteration of the maximal response is observed.
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   NMDA receptor antagonist

   Because of these psychotomimetic effects, NMDA receptor antagonists, especially phencyclidine, ketamine, and dextromethorphan, are used as recreational drugs.
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   IC50

   IC50 values can be used to compare the potency of two antagonists. ... In this type of assay, a single concentration of radioligand (usually an agonist) is used in every assay tube.
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   Schild regression

   Agonists and antagonists can have various effects on ligand binding. ... A radio-receptor assay requires the separation of the bound from the free ligand.
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   H2 antagonist

   H2 antagonist are used in the treatment of dyspepsia, although they have largely been surpassed in popularity by the more effective proton pump inhibitors. ... H2 receptor antagonists
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   Cannabinoid Receptor 1 Antagonists: Drug Discovery and Development

   Therefore, CB1 antagonists might indirectly inhibit the dopamine-mediated rewarding properties of food. ... In Figure 4 rimonabant is used as an example.
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   Cannabinoid receptor antagonist

   Therefore, CB1 antagonists might indirectly inhibit the dopamine-mediated rewarding properties of food. ... In Figure 4 rimonabant is used as an example.
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   Discovery and development of Cannaboid Receptor 1 Antagonists

   Therefore, CB1 antagonists might indirectly inhibit the dopamine-mediated rewarding properties of food. ... In Figure 4 rimonabant is used as an example.
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   Discovery and development of Cannabinoid Receptor 1 Antagonists

   Therefore, CB1 antagonists might indirectly inhibit the dopamine-mediated rewarding properties of food. ... In Figure 4 rimonabant is used as an example.
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    Ketamine

    It is primarily used for the induction and maintenance of general anesthesia, usually in combination with some sedative drug. ... NMDA receptor antagonists

Explore the following pages on Powerset:

• Receptor antagonist,
• NMDA receptor antagonist,
• IC50,
• Schild regression,
• H2 antagonist,
• Cannabinoid Receptor 1 Antagonists: Drug Discovery and Development,
• Cannabinoid receptor antagonist,
• Discovery and development of Cannaboid Receptor 1 Antagonists,
• Discovery and development of Cannabinoid Receptor 1 Antagonists,
• Ketamine