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epigenetic change to modify
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Epigenetics
The stability and heritability of states of larger chromosomal regions are often thought to involve positive feedback where modified nucleosomes recruit enzymes that similarly modify nearby nucleosomes. ... Prions can be viewed as epigenetic agents capable of inducing a phenotypic change without modification of the genome. -
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Secreted frizzled-related protein 1
Methylation-specific PCR (MSP) is able to detect this epigenetic change and could be used for cancer detection. -
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Paramutation
Rassoulzadegan M et al (2006) RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse. -
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Reelin
They change their mode of migration from tangential to radial, and begin using the radial glia fibers as their guides. ... "On the epigenetic regulation of the human reelin promoter". -
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Cancer
Known mechanisms of epigenetic change include DNA methylation, and methylation or acetylation of histone proteins bound to chromosomal DNA at specific locations. ... Mutations in proto-oncogenes, which are the normally quiescent counterparts of oncogenes, can modify their expression and function, increasing the amount or activity of the product protein. -
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Computational epigenetics
A substantial amount of bioinformatic research has been devoted to the prediction of epigenetic information from characteristics of the genome sequence. -
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Epigenetic landscape
Epigenetic modifications include methylation of cytosine residues of DNA and post-translational modifications of the histone proteins associated with the DNA strand. -
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Epigenetic code
The epigenetic code is hypothesized to be a defining code in every eukaryotic cell consisting of the specific epigenetic modification in each cell. -
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Long noncoding RNA
NcRNAs modulate the function of transcription factors by several different mechanisms, including functioning itself as a co-regulator, modifying transcription factor activity, or by regulating the association and activity of co-regulators. ... Long ncRNAs in epigenetic regulation -
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Long non-coding RNA
NcRNAs modulate the function of transcription factors by several different mechanisms, including functioning itself as a co-regulator, modifying transcription factor activity, or by regulating the association and activity of co-regulators. ... Long ncRNAs in epigenetic regulation
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epigenetic change to modify