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Transcription factor
Diabetes A rare form of diabetes called MODY (Maturity onset diabetes of the young) can be caused by mutations in hepatocyte nuclear factors (HNFs) or insulin promoter factor-1 (IPF1/Pdx1).
Glucokinase
Loss of function mutations cause diabetes
Maturity onset diabetes of the young
Maturity onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes caused by mutations in an autosomal dominant gene (sex independent, i.e. inherited from any of the parents) disrupting insulin production.
Maturity onset diabetes of the young
A form of permanent neonatal diabetes has been caused by homozygous mutations in the GCK gene.
Maturity onset diabetes of the young
More severe mutations in the KCNJ11 gene can cause early-onset diabetes which does not respond to the sulfonylurea drugs, as well as a syndrome of developmental delay and neurological features called the DEND syndrome.
ATP-Sensitive Potassium Channels
"Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.".
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Olanzapine
But Lilly was concerned that Zyprexa’s sales would be hurt if the company was more forthright about the fact that the drug might cause unmanageable weight gain or diabetes, according to the documents, which cover the period 1995 to 2004.
Adverse effect (medicine)
Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)
Eli Lilly controversies
But Lilly was concerned that Zyprexa’s sales would be hurt if the company was more forthright about the fact that the drug might cause unmanageable weight gain or diabetes, according to the documents, which cover the period 1995 to 2004.
Adverse drug reaction
Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)
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Diabetes mellitus
A small proportion of people with type 1 diabetes carry a mutated gene that causes maturity onset diabetes of the young (MODY).
University of Michigan Health System
One of two lead institutions in the Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics (FUSION) study group that recently discovered 4 new genes causing Type II Diabetes.
Survival of the Sickest (book)
Moalem argues that some of the "bad genes" which cause diabetes, for example, helped our ancestors survive at some point in our evolutionary history.
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Adverse effect (medicine)
Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)
Adverse drug reaction
Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)
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Acromegaly
In rare cases, octreotide treatment can cause diabetes.
Michael Somogyi
He took a special interest in diabetic patients and in 1938, at a meeting of the medical society in St. Louis to the theme of “unstable, severe diabetic patients”, Somogyi first presented his theory that insulin treatment in itself might cause unstable diabetes.
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Steroid diabetes
The most common glucocorticoids which cause steroid diabetes are prednisone and dexamethasone given systemically in "pharmacologic doses" for days or weeks.
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Denise Faustman
Type 1 Autoimmune Diabetes is caused by rogue T cells that attack healthy tissue.
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Nutrition
The state of obesity clearly contributes to insulin resistance, which in turn can cause type 2 diabetes.
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Alloxan
Alloxan does not cause diabetes in humans.
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Diabetes mellitus
Diseases associated with excessive secretion of insulin-antagonistic hormones can cause diabetes (which is typically resolved once the hormone excess is removed).
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Hepatocyte nuclear factors
Variants of the genes can cause several relatively rare forms of MODY, an inherited, early onset form of diabetes.
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Ljungan virus
The Ljungan virus causes diabetes, neurological disease, myocarditis and disease and deaths in pregnant laboratory mice and their offspring.
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The Alcat Test
Food intolerance has been shown to cause migraines, aching joints, fatigue, urticaria, celiac disease, diabetes, gastrointestinal disorders, eczema, hyperactivity/ADD, nausea, stomach pain, gas, cramps, bloating, vomiting, heartburn, diarrhea, irritability, nervousness, asthma and obesity.
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Maturity onset diabetes of the young
A newly identified and potentially treatable form of monogenic diabetes is the neonatal diabetes caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel.
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French paradox
Trans fats are well known to cause diabetes, heart disease and macular eye disease.
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Bcl-2
The autoimmune disease, type 1 diabetes can be caused by defective apoptosis, which leads to aberrant T cell AICD and defective peripheral tolerance.
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Survival of the Sickest (book)
The hypothesis that diabetes, which develops later in life, might be caused by a false environmental pressure during or before pregnancy is explored in this book.
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Frederick Banting
The work of Naunyn, Minkowski, Opie, Schafer, and others had indicated that diabetes was caused by lack of a protein hormone secreted by the Islets of Langerhans in the pancreas.
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IPEX (syndrome)
Early age onset of this disease in males causes severe enlargement of the secondary lymphoid organs, insulin dependent diabetes, eczema, food allergies, and infections.
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Juvenile Diabetes Research Foundation
Autoimmunity: A key part of JDRF's research is aimed at stopping or reversing the immune system response that causes diabetes: the attack on insulin-secreting cells in the pancreas.
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